abstract：BACKGROUND AND OBJECTIVES:There have been few reports on the objective assessment of quality of life (QOL) in patients with gastric cancer following palliative operations. The benefit of a palliative operation for survival and QOL of patients with gastric cancer is not clear. METHODS:Survival and hospital-free surviva...

journal_title：Journal of surgical oncology

authors： Ouchi K,Sugawara T,Ono H,Fujiya T,Kamiyama Y,Kakugawa Y,Mikuni J,Yamanami H

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Recent advancements in the technology of cryosurgery along with the development and refinement of intraoperative ultrasound have led to a feasible alternative for some patients with unresectable hepatic malignancy. This paper reports our first year's experience with cryosurgical ablation of un...

journal_title：Journal of surgical oncology

authors： Dale PS,Souza JW,Brewer DA

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Peritoneal papillary serous carcinoma (PPSC) is histologically and clinically similar to stage III-IV ovarian papillary serous carcinoma (OPSC). The purpose of this study was to investigate the clinical findings, treatment, and outcome of PPSC patients compared with stage III-IV OPSC patients....

journal_title：Journal of surgical oncology

authors： Piura B,Meirovitz M,Bartfeld M,Yanai-Inbar I,Cohen Y

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Immunohistochemical methods were used to study Tenascin (TN) expression in invasive duct cell carcinoma (IDCC) of the breast and its established prognostic factors. METHODS:We studied 115 patients with IDCC. The mean patient age was 62 years; all tumors were graded according to Scarf-Bloom an...

journal_title：Journal of surgical oncology

authors： Iskaros BF,Hu X,Sparano JA,Fineberg SA

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Primary retroperitoneal tumors constitute a rather uncommon disease with an incidence of 2 in 100,000. Local recurrence after surgical resection is reported between 60% and 90% at 10 yr. The aim of this study was to present the problem of satellite tumors around the main tumor mass and their p...

journal_title：Journal of surgical oncology

authors： Voros D,Theodorou D,Ventouri K,Prachalias A,Danias N,Gouliamos A

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Several molecular biology techniques are utilized to study changes in gene expression during the genesis of human tumors. Our objective was to identify genes that showed altered expression between normal brain tissue (NBT) and glioblastoma multiforme tumor tissue (GMTT). METHODS:The technique...

journal_title：Journal of surgical oncology

authors： Sehgal A,Boynton AL,Young RF,Vermeulen SS,Yonemura KS,Kohler EP,Aldape HC,Simrell CR,Murphy GP

更新日期：1998-04-01 00:00:00

abstract：:Follicular thyroid carcinoma, initially presenting as spinal cord compression due to metastatic lesions, is a less reported event. We present two cases of well-differentiated thyroid carcinoma that led to spinal cord compression. A thorough search of the literature revealed only five similar cases. We summarize the cl...

journal_title：Journal of surgical oncology

authors： Goldberg H,Stein ME,Ben-Itzhak O,Duek D,Ravkin A,Gaitini D

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:It has been estimated that approximately 5% of middle and low rectal adenocarcinomas are amenable to local therapy. However, these treatment modalities are limited by their failure to identify and treat regional nodal metastases. METHODS:This study was undertaken to evaluate the role of tumor...

journal_title：Journal of surgical oncology

authors： Zenni GC,Abraham K,Harford FJ,Potocki DM,Herman C,Dobrin PB

更新日期：1998-02-01 00:00:00

abstract：:Brachytherapy, the direct application of a radioactive isotope into the tumor bed, delivers a high dose to the tumor as compared to the surrounding normal tissue. Interstitial brachytherapy, the placement of the isotope into a tumor bed where no lumen exists, has been described but is utilized infrequently in clinical...

journal_title：Journal of surgical oncology

authors： Gaspar LE

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Several tumor-related antigen peptides that are recognized by autologous cytolytic T cells (CTL) have been reported. However, most human solid tumors, including gastric carcinoma, are only weakly immunogenic. In this study, we focused on interleukin (IL)-12 and interferon-gamma (IFN-gamma) as ...

journal_title：Journal of surgical oncology

authors： Katano M,Nakamura M,Kuwahara A,Fujimoto K,Matsunaga H,Miyazaki K,Morisaki T

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Tumor angiogenesis is receiving increased attention as a prognostic factor and also as a possible target for new anticancer agents. We investigated whether extent of vascular endothelial growth factor (VEGF) mRNA expression correlated with degree of neovascularization, and whether this express...

journal_title：Journal of surgical oncology

authors： Anan K,Morisaki T,Katano M,Ikubo A,Tsukahara Y,Uchiyama A,Kuroki S,Tanaka M,Torisu M

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Retinoids are metabolized in human intestinal epithelial cells to all-trans retinoic acid; however, it is unknown whether these cells express retinoid receptors, and whether sensitivity or resistance to the hormone is associated with a particular pattern of expression of retinoid-responsive ge...

journal_title：Journal of surgical oncology

authors： Waliszewski P,Waliszewska MK,Gupta M,Milsom JW,Hurst RE

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Development of second primary carcinomas after thoracic esophagectomy has become of much concern, because recently the prognosis of thoracic esophageal carcinoma after esophagectomy with extended lymph node dissection has been improving. We report our experience of diagnosing and treatment sec...

journal_title：Journal of surgical oncology

authors： Murata S,Kato H,Tamura H,Tachimori Y,Watanabe H,Yamaguchi H,Nakanishi Y

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The median of pO2 values in tumor measured by Eppendorf "Histograph" with a needle-type electrode has been used as a prognostic indicator in cancer patients. However, it is not established that a pretreatment measured pO2 value can be used as a universal predictor of local control probability,...

journal_title：Journal of surgical oncology

authors： Nozue M,Lee I,Yuan F,Teicher BA,Brizel DM,Dewhirst MW,Milross CG,Milas L,Song CW,Thomas CD,Guichard M,Evans SM,Koch CJ,Lord EM,Jain RK,Suit HD

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:This study aims to clarify clinicopathologic characteristics of synchronous primaries of the extrahepatic bile duct and gallbladder. Understanding multiplicity and its histologic confirmation is an important step for successful surgical management. METHODS:Of the 190 cases of resection of bil...

journal_title：Journal of surgical oncology

authors： Kurosaki I,Watanabe H,Tsukada K,Hatakeyama K

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Argyrophilic nucleolar organizer regions (AgNORs) have been recently identified as a marker of proliferative index in various tumors. These were evaluated in 46 patients with primary breast carcinoma and were correlated with clinical prognostic parameters of breast cancer. Ten patients with be...

journal_title：Journal of surgical oncology

authors： Kumar A,Kushwaha AK,Kumar M,Gupta S

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Malignant cartilage tumors demonstrate chemotherapeutic resistance through undetermined mechanisms. P-glycoprotein is the protein product of the multiple drug resistance gene 1 (MDR-1) and confers multidrug chemotherapeutic resistance in a variety of malignancies. METHODS:MDR-1 expression was...

journal_title：Journal of surgical oncology

authors： Rosier RN,O'Keefe RJ,Teot LA,Fox EJ,Nester TA,Puzas JE,Reynolds PR,Hicks DG

更新日期：1997-06-01 00:00:00

abstract：:We reviewed the literature concerning the effect of extended lymph node dissection on survival in patients with gastrointestinal cancer. Most retrospective and/or prospective nonrandomized comparative studies have claimed that extended lymph node dissection significantly improves survival rate in patients with esophag...

journal_title：Journal of surgical oncology

authors： Noguchi M,Miyazaki I

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Immunoreactivity for p53 tumor suppressor gene product is commonly found in human malignancies and some premalignant lesions, but its role in cancer development and its value as a marker of tumor biologic behavior is still unclear. OBJECTIVES:This study was undertaken to assess p53 immunoexpression in esoph...

journal_title：Journal of surgical oncology

authors： Chaves P,Pereira AD,Pinto A,Oliveira AG,Queimado L,Gloria L,Cardoso P,Mira FC,Soares J

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Based on the promising results of EAP (etoposide, doxorubicin, and cisplatin) combination, a phase II study of modified EAP combination was performed in patients with advanced gastric cancer to evaluate the response, toxicity, and survival. METHOD:Fifty-two consecutive patients with measurable or evaluable ...

journal_title：Journal of surgical oncology

authors： Içli F,Karaoguz H,Akbulut H,Dinçol D,Demirkazik A,Cay F

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:In the United States, pulmonary adenocarcinomas have recently replaced squamous cell carcinomas as the most frequent type of lung cancer encountered. The incidence of pulmonary adenocarcinoma continued to increase worldwide. METHOD:To determine the roles of the transforming growth factor-beta 1 (TGF-beta 1)...

journal_title：Journal of surgical oncology

authors： Takanami I,Tanaka F,Hashizume T,Kodaira S

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Approximately 20% of patients with thyroid carcinoma have relapse. To evaluate the factors affecting their disease-free survival and prognosis, we studied 68 patients with recurrent differentiated thyroid carcinoma, ranging in age from 5 to 73 years (mean: 47.6 years). Three-fourths of patients were followed...

journal_title：Journal of surgical oncology

authors： Asakawa H,Kobayashi T,Komoike Y,Tamaki Y,Matsuzawa Y,Monden M

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:The most effective treatment for patients with esophageal small cell carcinoma has not yet been established because of the overall extremely poor prognosis regardless of the mode of treatment. The role of esophagectomy has been controversial in the management of patients with this disease. METHODS:The clini...

journal_title：Journal of surgical oncology

authors： Nishimaki T,Suzuki T,Nakagawa S,Watanabe K,Aizawa K,Hatakeyama K

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Since the majority of patients with early gastric cancer show long-term survival after surgery, a special attention must be directed to preserving gastric function in these patients. Little is known about the protocol of surgical treatment appropriate for early gastric cancer patients. This study was designe...

journal_title：Journal of surgical oncology

authors： Kitamura K,Yamaguchi T,Taniguchi H,Hagiwara A,Sawai K,Takahashi T

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:It was observed that new presentations of anaplastic carcinoma of the thyroid had become infrequent in the last two decades. METHODS:All cases of thyroid cancer seen at our centre between 1969-1993 (n = 2921) were classified as papillary 49%, follicular 34%, medullary 7.5%, anaplastic 4.7%, and other 4.8%. ...

journal_title：Journal of surgical oncology

authors： Agrawal S,Rao RS,Parikh DM,Parikh HK,Borges AM,Sampat MB

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:Evidence exists that estrogens influence the action of epidermal growth factor (EGF) and its receptor (EGF-R) at multiple levels. Estrogen and antiestrogen action on gastric and other gastrointestinal malignancies has been evaluated by several groups with conflicting results, and EGF-R has been implicated in...

journal_title：Journal of surgical oncology

authors： Koullias GJ,Kouraklis GP,Raftopoulos IS,Davaris PS,Papadopoulos SA,Golematis BC

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:Endometrial carcinoma is the most common gynecologic malignancy in developed countries, affecting an estimated 140,000 women. More than 32,000 women will be diagnosed with endometrial cancer this year in the United States, and approximately 6,000 will die from this disease. METHODS:Twenty consecutive patien...

journal_title：Journal of surgical oncology

authors： Geisler JP,Wiemann MC,Zhou Z,Miller GA,Geisler HE

更新日期：1996-10-01 00:00:00

abstract：:At present, limb-sparing surgery is the most appropriate and acceptable treatment available for sarcomas of the extremities, although the right balance between conservative therapy and maximum efficacy has yet to be found. A better knowledge of prognostic factors may help in planning the appropriate strategy for each ...

journal_title：Journal of surgical oncology

authors： Rossi CR,Foletto M,Alessio S,Menin N,D'Amore E,Rigon A,Lise M

更新日期：1996-09-01 00:00:00

abstract：:Ten children with locally advanced or recurrent tumors were treated on a Phase I/II study to assess the feasibility and toxicity of intraoperative radiotherapy (IORT) for primary and recurrent pediatric solid malignancies at high risk for local recurrence. Eligible patients include all primary and recurrent pediatric ...

journal_title：Journal of surgical oncology

authors： Zelefsky MJ,LaQuaglia MP,Ghavimi F,Bass J,Harrison LB

更新日期：1996-08-01 00:00:00

abstract：:Twenty-six patients with esophageal carcinoma at stage pT4 underwent esophagectomy with lymph node dissection leaving part of the tumor in adjacent organs. Several plastic catheters were fixed to the tumor bed and led to the outside of the thorax for postoperative brachytherapy. Using these catheters, the patients und...

journal_title：Journal of surgical oncology

authors： Kato H,Kagami Y,Tachimori Y,Watanabe H,Ikeda H

更新日期：1996-07-01 00:00:00

abstract：:A pharmacokinetic analysis of cis-diamminedichloroplatinum (II) (DDP) was conducted comparing low-dose daily bolus infusions, and high-dose drip infusions. Eight patients with gastric cancer were treated with low-dose daily bolus infusions of DDP to a total daily dose of 75 mg/m2 bid for 5 days. Four patients with eso...

journal_title：Journal of surgical oncology

authors： Kurihara N,Kubota T,Hoshiya Y,Otani Y,Ando N,Kumai K,Kitajima M

更新日期：1996-06-01 00:00:00

abstract：:The last two decades have seen great improvements in the management of patients with germ-cell tumors of the ovary. The initial treatment approach includes conservative surgery and cisplatin-based chemotherapy in most cases. At completion of chemotherapy, the role of second-look surgery remains questionable. We retros...

journal_title：Journal of surgical oncology

authors： Culine S,Lhomme C,Michel G,Leclere J,Duvillard P,Droz JP

更新日期：1996-05-01 00:00:00

abstract：:Breakdown of membrane phospholipids is a causative event leading to irreversible cell injury after ischemia and reperfusion insults, which might be one mechanism leading to liver tumor cell death after repeated arterial ischemia as well. After 2 hr of hepatic dearterialization followed by 30 min of reperfusion tumor p...

journal_title：Journal of surgical oncology

authors： Wang LQ,Persson BG,Xu N,Seidegård J,Jeppsson B,Bengmark S

更新日期：1996-04-01 00:00:00

abstract：:Preoperative radiological findings of nodal status in 74 patients, using endoscopic ultrasonography (EUS), computed tomography (CT), ultrasonography (US), and magnetic resonance imaging (MRI), were compared to histopathology reports following transthoracic total esophagectomy with radical lymphadenectomy (TTE), involv...

journal_title：Journal of surgical oncology

authors： Chandawarkar RY,Kakegawa T,Fujita H,Yamana H,Hayabuthi N

更新日期：1996-03-01 00:00:00

abstract：:Metastasis to the breast is uncommon, with an incidence of 0.5-3%. Alveolar soft part sarcoma is rare, accounting for < 1% of malignant soft tissue tumors, which are themselves unusual. Excluding contralateral breast and hematologic malignant disease, the primary lesion in most cases of metastasis to the breast is mel...

journal_title：Journal of surgical oncology

authors： Hanna NN,O'Donnell K,Wolfe GR

更新日期：1996-02-01 00:00:00

abstract：:Oncogenes, tumor suppressor genes, and growth factors are being explored as to their role in the initiation and progression of most neoplasms, but little information exists on the expression of oncoproteins or growth factors in adenocarcinoma of the duodenum or ampulla of Vater. This report covers expressions of p53, ...

journal_title：Journal of surgical oncology

authors： Zhu L,Kim K,Domenico DR,Appert HE,Howard JM

更新日期：1996-02-01 00:00:00

abstract：:To define more precisely the prognostic index for patients with primary carcinoma of the gallbladder in Taiwan, we retrospectively reviewed the data of 74 patients with gallbladder carcinoma treated over a period of 15 years, from 1979 to 1993. Of these patients, 75% had Nevin stage V gallbladder cancer. The most comm...

journal_title：Journal of surgical oncology

authors： Chao TC,Wang CS,Jeng LB,Jan YY,Chen MF

更新日期：1996-01-01 00:00:00

abstract：:Recently we resected and reconstructed the sternum in two female patients with thyroid carcinoma metastatic to the sternum. Histological diagnosis of the metastatic lesion was follicular carcinoma in the first case and papillary carcinoma in the second case. Reconstruction of the sternum was accomplished by using an a...

journal_title：Journal of surgical oncology

authors： Ozaki O,Kitagawa W,Koshiishi H,Sugino K,Mimura T,Ito K

更新日期：1995-12-01 00:00:00

abstract：:Between 1989 and 1991, 150 patients with ovarian cancer were treated with chemotherapy, including cisplatin, in the Tokai Ovarian Tumor Study Group. Of these patients, 25 underwent cytoreductive surgery with lymphadenectomy, including removal of either pelvic or para-aortic lymph nodes, and 36 underwent both lymphaden...

journal_title：Journal of surgical oncology

authors： Kikkawa F,Ishikawa H,Tamakoshi K,Suganuma N,Mizuno K,Kawai M,Arii Y,Tamakoshi A,Kuzuya K,Tomoda Y

更新日期：1995-12-01 00:00:00

abstract：:Prophylactic intravesical chemotherapy (IVC) reduces recurrence rates of superficial transitional cell carcinoma (TCC) of the urinary bladder. The patient cohort existed of 86 individuals (stage TaN0M0 or T1N0M0) superficial carcinoma of various grades of malignancy. Following initial transuretheral resection or diagn...

journal_title：Journal of surgical oncology

authors： Pavlotsky A,Eidelman A,Barak F,Walach N,Horn Y

更新日期：1995-11-01 00:00:00